protothecosis


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protothecosis

 [pro″to-the-ko´sis]
an infection caused by organisms of the genus Prototheca, especially P. wickerhamii or P. zopfii, varying from cutaneous and subcutaneous lesions to systemic invasion involving several internal organs, which may occur as an opportunistic infection or as a result of traumatic implantation of the pathogen into the tissues.

pro·to·the·co·sis

(prō'tō-thē-kō'sis),
A rare verrucous cutaneous infection, olecranon bursitis, or disseminated disease caused by Prototheca zopfii and Prototheca wickerhamii.

protothecosis

/pro·to·the·co·sis/ (-the-ko´sis) infection caused by organisms of the genus Prototheca, varying from cutaneous lesions to systemic invasion, occurring as an opportunistic infection or as a result of traumatic implantation of organisms into the tissues.

protothecosis

granulomatous panuveitis, enterocolitis, mastitis, dermatitis or a systemic spread of infection with the alga prototheca.
References in periodicals archive ?
Cutaneous protothecosis is an uncommon indolent condition occurring primarily in immunocompromised individuals.
Cutaneous protothecosis usually presents as an erythematous plaque that can be vesiculobullous or, less commonly, ulcerative, with crusting and purulent discharge (Figure 1).
4,12) The typical clinical course of cutaneous protothecosis is chronic and indolent.
2) Although protothecosis can be diagnosed on biopsy, culture of the organism on a media such as Sabouraud dextrose agar is required for definitive diagnosis.
Some authors have described a successful treatment on localized protothecosis with voriconazole (6).
This association is probably the result of disseminated protothecosis in severely immuno-compromised patients, and the alga may cross digestive or cutaneous barriers.
Disseminated protothecosis is currently rare but, due to the algae's ubiquitous nature, increasing use of immunosuppressive therapy, and increasing incidence of hematologic malignancy, Prototheca spp.
Protothecosis in patients with cancer: case series and literature review.
Protothecosis has been reported in both immunocompromised and immunocompetent individuals, and clinical presentations of infection include focal or disseminated, chronic cutaneous/subcutaneous infection,[5,6] bursitis,[1] and, rarely, systemic infection.
The diagnosis of protothecosis is generally made by direct identification of the organism in histologic sections or by culture of the organism from infected tissue.
In general, protothecosis does not resolve spontaneously.
Disseminated cutaneous protothecosis in an immunocompromised host: a case report and literature review.