protoporphyrinogen

protoporphyrinogen

/pro·to·por·phy·rin·o·gen/ (-por″fĭ-rin´ŏ-jen) any of fifteen isomers of a porphyrinogen derivative, one of which is an intermediate produced from coproporphyrinogen in heme synthesis.
References in periodicals archive ?
A R59W mutation in human protoporphyrinogen oxidase results in decreased enzyme activity and is prevalent in South Africans with variegate porphyria.
It inhibits a key step in chlorophyll biosynthesis, called protoporphyrinogen IX oxidase (PPO), resulting in fast, effective control of broadleaf weeds.
5 mouse protoporphyrinogen oxidase Al176856 Cytochrome P450 1b1 1.
That VP is related causally to deficient activity in the penultimate enzyme of the haem biosynthetic pathway, protoporphyrinogen oxidase (PPOX), was first shown by Brenner and Bloomer in 1980.
Allosteric inhibition of human lymphoblast and purified porphobilinogen deaminase by protoporphyrinogen and coproporphyrinogen: a possible mechanism for the acute attack of variegate porphyria.
Carfentrazone-ethyl is an inhibitor of protoporphyrinogen oxidase (PPO).
This has traditionally depended on analysis of metabolites in urine and feces with, more recently, measurement of protoporphyrinogen oxidase when these are uninformative.
Plasma 804 Sandberg and Elder: Diagnosing Acute Porphyrias fluorescence scanning and fecal porphyrin analysis for the diagnosis of variegate porphyria: precise determination of sensitivity and specificity with detection of protoporphyrinogen oxidase mutations as a standard.
It is a protoporphyrinogen oxidase (PPO) inhibitor in a new class of soybean herbicides.
Variegate porphyria (VP) (1) is the autosomal dominant disorder associated with deficiency of the enzyme protoporphyrinogen oxidase (PPOX), the penultimate enzyme of the heme synthetic pathway (1).
Variegate porphyria (VP) is characterized by decreased activity of protoporphyrinogen oxidase (PPOX), the penultimate enzyme in the heme biosynthetic pathway.
Coproporphyrinogen oxidase, protoporphyrinogen oxidase, and ferrochelatase activities were assayed using lymphocytes, according to the methods reported previously (13-15).