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Protoporphyrin IX

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protoporphyrin IX
n.
A porphyrin derivative that combines with ferrous iron to form the heme of hemoglobin and with ferric or ferrous iron to form the prosthetic groups of substances such as myoglobin, catalase, and the cytochromes.

Protoporphyrin IX
Protoporphyrin IX is a protein. The measurement of this protein is useful for the assessment of iron status. Hemoglobin consists of a complex of a protein plus heme. Heme consists of iron plus protoporphyrin IX. Normally, during the course of red blood cell formation, protoporphyrin IX acquires iron, to generate heme, and the heme becomes incorporated into hemoglobin. However, in iron deficiency, protophoryrin IX builds up.


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Moreover, our experiments suggested that a substance known as protoporphyrin IX was important in regulating frataxin expression.
Kolling analyzed the Soret band energies of nickel protoporphyrin IX dimethyl ester in a set of 16 solvents with varying polarities and varying polarizabilities and concluded, by grouping solvents according to the Chastrette-Purcell generalized classification system, that the dependence of the Sore t band energies upon solvent polarizability effects is insignificant (Kolling 1989).
Detection of squamous cell carcinoma of the oral cavity by imaging 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
 
 
 
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