protoporphyrin


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Related to protoporphyrin: Zinc Protoporphyrin

protoporphyrin

 [pro″to-por´fĭ-rin]
a porphyrin whose iron complex united with protein occurs in hemoglobin, myoglobin, and certain respiratory pigments. It is accumulated and excreted excessively in the feces in erythropoietic protoporphyria and variegate porphyria.

protoporphyrin

/pro·to·por·phy·rin/ (-por´fĭ-rin) any of several porphyrin isomers, one of which is an intermediate in heme biosynthesis; it is accumulated and excreted excessively in feces in erythropoietic protoporphyria and variegate porphyria.

protoporphyrin

(prō′tō-pôr′fə-rĭn)
n.
A metal-free porphyrin, C34H34N4O4, that combines with ferrous iron to form the heme group in hemoglobin and myoglobin, and with ferric iron to form the hemin group in catalase and some cytochromes.

protoporphyrin

[prō′tōpôr′firin]
Etymology: Gk, protos + porphyros
a kind of porphyrin that combines with iron and protein to form various important organic molecules, including catalase, hemoglobin, and myoglobin. See also heme.

protoporphyrin

A porphyrin occurring in the course of the synthesis of HAEMOGLOBIN. Excess of this porphyrin, protoporphyria, causes intense itching, swelling and redness of the skin on exposure to sunlight and leads to a strikingly weatherbeaten appearance.

Protoporphyrin

A precursor molecule to the porphyrin molecule.
Mentioned in: Porphyrias

protoporphyrin

a porphyrin whose iron complex united with protein occurs in hemoglobin, myoglobin and certain respiratory pigments.

protoporphyrin III
combines with 4 moles of iron to form the heme moiety of hemoglobin.
References in periodicals archive ?
Although an observational study of Eurasian Blue Tits (Cyanistes caeruleus) has found a positive association between more widely distributed protoporphyrin pigment spots and male provisioning rates (Sanz and Garcia-Navas 2009), direct experimental testing is needed to determine whether this relationship is causal.
methyl aminolevulinate acid: PpIX, protoporphyrin IX; ROS, reactive oxygen species; CI, combination index; DRI, dose reduction index; ARE, antioxidant response element; HO-1, heme oxygenase 1; Nrf2, nuclear factor E2-related factor 2.
The team identified Tin Protoporphyrin (SnPP) as a candidate for the prevention of salmonella infection.
Plasma ferritin levels below 12 [micro]g/L in the first three months of infancy and protoporphyrin levels below 35 [micro]g/L in addition to ferritin level in the first 6 months of infancy are considered to be more significant compared to a Hb level below 11 g/dL for the diagnosis of iron deficiency anemia (4,6,7).
Excessive plasma protoporphyrin is deposited in the skin causing photosensitivity triggered by light wavelengths around 400nm (1).
The major pigment of brown eggshells is protoporphyrin (Lang and Wells, 1987).
N-alkylporphyrins distort or bend protoporphyrin IX, inhibiting the production of heme (as in hemoglobin).
Kennedy JC, Pottier RH, Pross DC: Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience.
They oxidize several substrates in the presence of hydrogen peroxide and usually contain a protoporphyrin IX prosthetic group [8] and several authors have reviewed its properties and physiological roles in fruits and vegetables.
Less bone lead, urinary delta-aminolevulinic acid, zinc protoporphyrin, and DMSA-chelatable lead (all markers of lead accumulation or toxicity) are found in ALAD-2 patients (85).
Also usually included is a serum iron (SI), total iron binding capacity (TIBC), percent transferrin saturation (TS), and free/zinc erythropoietic protoporphyrin (FEP/ZPP) level.
HO-1 was induced in cultured mTALH cells by treatment with cobalt protoporphyrin (CoPP), hemin (50 [micro]M) or by transfection with a plasmid containing the human HO-1 isoform.