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protofibril

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protofibril [pro″to-fi´bril]
the first elongated unit appearing in formation of any type of fiber.
protofibril
the first elongated unit appearing in formation of any type of fiber.
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All three proteins also produce nonfibrillar oligomers that may be assembly intermediates, analogous to the A[beta] protofibril.
Review: structure of amyloid fibril in diseases by Ghahghaei, Arezou; Faridi, Nasim / Journal of Biomedical Science and Engineering (JBiSE)
[2]Pathogenesis of Alzheimer's disease and amyloid beta-peptide protofibrils Accumulation of amyloid beta-peptide in the brain is believed to play a key role in the development of Alzheimer's disease.
Eisai and BioArctic Neuroscience Enter Exclusive Licensing Agreement ... by JCN Newswires
As the process continues, these oligomers grow larger, becoming increasingly insoluble entities called protofibrils and fibrils.
Part 3: 2004-2005 AD research advances: new discoveries, new insights by Pamphlet by: National Institute on Aging
 
 
 
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