Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to prothrombinase: Stuart-Prower factor
2. the complex formed between activated factor x and calcium, phospholipid, and modified factor v; it can cleave and activate prothrombin to thrombin in the common pathway of coagulation. The term is sometimes used to refer specifically to the active enzyme center of the complex, which is activated factor x.
in the clotting of blood, also known as: Stuart factor, Stuart-Prower factor, prothrombase, and prothrombinase. Its active form, factor Xa (EC 18.104.22.168), is formed from factor X by limited proteolysis and assists in the conversion of prothrombin to thrombin. A deficiency of factor X will lead to impaired blood coagulation.
1. the complex of activated coagulation factor X and calcium, phospholipid, and modified factor V; it can cleave and activate prothrombin to thrombin.
2. sometimes specifically the active enzyme center of the complex, activated factor X.
An enzyme complex that catalyzes the hydrolysis of prothrombin to thrombin.
prothrombinase; factor X blood enzyme that hydrolyses prothrombin, forming thrombin
n (complete thromboplastin, direct activator of prothrombin, extrinsic prothrombin activator), an inferred direct activator of prothrombin common to tissue and plasma coagulation systems. See also factor V.
thromboplastin; tissue factor, factor III.