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prothrombinase

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prothrombinase /pro·throm·bin·ase/ (-throm´bin-ās)
1. the complex of activated coagulation factor X and calcium, phospholipid, and modified factor V; it can cleave and activate prothrombin to thrombin.
2. sometimes specifically the active enzyme center of the complex, activated factor X.

pro·throm·bin·ase (pr-thrmb-ns, -nz)
n.
An enzyme that catalyzes the hydrolysis of prothrombin to thrombin. Also called factor X, Stuart factor.

prothrombinase [pro-throm´bin-ās]
2. the complex formed between activated factor x and calcium, phospholipid, and modified factor v; it can cleave and activate prothrombin to thrombin in the common pathway of coagulation. The term is sometimes used to refer specifically to the active enzyme center of the complex, which is activated factor x.

prothrombinase (prōthrom´binās),
n (complete thromboplastin, direct activator of prothrombin, extrinsic prothrombin activator), an inferred direct activator of prothrombin common to tissue and plasma coagulation systems. See also factor V.

prothrombinase
thromboplastin; tissue factor, factor III.


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5) Subsequent fixation of the prothrombinase complex and commencement of the coagulation cascade follows, ultimately leading to a platelet-rich thrombus within the coronary artery, over the disrupted plaque.
1]) and increased concentration of glycoprotein II (GPII) and platelet prothrombinase activity.
[FIGURE 3 OMITTED] POLYMORPHISMS IN THE PROTEIN C PATHWAY Factor V Leiden and Activated Protein C Resistance Activated factor V (factor Va) is a cofactor protein in the prothrombinase complex that, together with the serine protease factor Xa, is responsible for conversion of prothrombin to the active enzyme thrombin.
 
 
 
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