prothionamide


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prothionamide

Protionamide, a drug used in the treatment of TUBERCULOSIS resistant to commoner drugs.
References in periodicals archive ?
A case of DRESS syndrome induced by the antituberculosis drugs, prothionamide, and para-aminosalycilic acid.
MDR, KMRC 00116-00250, pathogenic-resistant to isoniazid, rifampicin, streptomycin, and pyrazinamide; XDR, KMRC 00203- 00197, pathogenic-resistant to isoniazid, rifampicin, ethambutol, kanamycin, ofloxacin, rifabutin and amikacin, but susceptible to capreomycin, streptomycin, moxifloxacin, prothionamide, p-aminosalicylic, and cycloserine.
This so called 'Bangladesh' regimen consists of high-dose isoniazid, high-dose gatifloxacin, kanamycin, prothionamide, ethambutol, pyrazinamide and clofazimine given for only 9 months and is now being compared with the standard 18 --24-month regimen in The Evaluation of a Standardised Treatment Regimen of Anti-Tuberculosis Drugs for Patients with Multidrug-Resistant Tuberculosis (STREAM), an International Union Against Tuberculosis and Lung Disease sponsored, non-inferiority clinical trial.
In a trial in Malta rifampicin, dapsone, prothionamide, and isoniazid therapy for a total of 18-24 months prior to discontinuation was claimed to result in no clinical relapse over a 4-year follow-up.
In 2014, she relapsed again but with an XDR strain and was prescribed pyrazinamide, cycloserine, PAS, amoxicillin/clavulanate, capreomycin, levofloxacin, prothionamide, clarithromycin, and clofazimine.
leprae he had developed a regimen for the treatment of leprosy utilising Isoprodian (a combination of prothionamide, dapsone and isoniazid) and rifampicin.
These agents include ethionamide (ETH) or prothionamide, KM or AMK, terizidone/cycloserine (CS), capreomycin (CP), viomycin (VM) and para-aminosalicylic acid (PAS).
In the Philippines, the standardized treatment regimen for MDR TB is pyrazinamide, kanamycin, levofloxacin, prothionamide, and cycloserine; the intensive phase lasts [greater than or equal to] 6 months and the continuation phase an additional [greater than or equal to] 12 months.
After psychosocial counseling and health education sessions, the boy, with his family's agreement, consented to daily outpatient treatment with isoniazid (400 mg), ethambutol (800 mg), pyrazinamide (1,600 mg), prothionamide (500 mg), moxifloxacin (400 mg), capreomycin (750 mg), and clofazimine (100 mg) beginning in December 2013.
Third, we identified patients who had taken at least 1 prescription consisting of [greater than or equal to] 3 anti-TB drugs used simultaneously for at least 120 days during a 180-day period; these drugs were isoniazid, ethambutol, rifampin, pyrazinamide, amikacin, kanamycin, streptomycin, ciprofloxacin, ofloxacin, moxifloxacin, levofloxacin, prothionamide, clarithromycin, and thioridazine (20,21).
0 35 65 Cycloserine Susceptible 50 78 22 Prothionamide Susceptible <1.