proteoglycan


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Related to proteoglycan: Glycosaminoglycans, Heparan Sulfate Proteoglycan

proteoglycan

 [pro″te-o-gli´kan]
any of a group of glycoproteins found primarily in connective tissue and formed of subunits of glycosaminoglycans (long polysaccharide chains containing amino sugars) linked to a protein core like bristles on a bottle brush. Hydrated proteoglycans form the highly viscous fluid of mucus and the matrix of the intercellular ground substance of connective tissue. Called also mucopolysaccharide.

pro·te·o·gly·can

(prō'tē-ō-glī'kan),
A glycoaminoglycans (mucopolysaccharides) bound to protein chains in covalent complexes; occur in the extracellular matrix of connective tissue.

proteoglycan

/pro·teo·gly·can/ (pro″te-o-gli´kan) any of a group of polysaccharide-protein conjugates present in connective tissue and cartilage, consisting of a polypeptide backbone to which many glycosaminoglycan chains are covalently linked; they form the ground substance in the extracellular matrix of connective tissue and also have lubricant and support functions.

proteoglycan

(prō′ē-ō-glī′kən)
n.
Any of various glycoproteins that have glycosaminoglycan chains attached by covalent bonds to the protein, usually found in the extracellular matrix of connective tissue.

pro·te·o·gly·can

(prō'tē-ō-glī'kan)
Glycoaminoglycans bound to protein chains in covalent complexes; found in extracellular matrix of connective tissue.

proteoglycan

any of a group of glycoproteins found primarily in connective tissue and formed of subunits of glycosaminoglycans (long polysaccharide chains containing amino sugars) linked to a protein core like bristles on a bottle brush. Hydrated proteoglycans form the highly viscous fluid of mucus and the matrix of the intercellular ground substance of connective tissue. Called also mucopolysaccharide.
References in periodicals archive ?
The proteoglycans in ECM serve as a bridge between cells and matrix, and contributes to construction of ECM by affecting collagens.
Chemical and biochemical aspects of the glycosaminoglycans and proteoglycans in health and disease.
Molecular characterization of chicken syndecan-2 proteoglycan.
Two sequence-specific peptide antisera (LF-15 and LF-30) generated against synthetic peptides corresponding to amino acids 11-24 and 5-17 of the human core proteins of 2 small leucine-rich proteoglycans, biglycan and decorin, were used to characterize territorial or interterritorial cartilage matrices.
But the Albany experiments were apparently the first to use proteoglycans extracted from actual chicken skin.
Although scientists still don't know why the adult brain begins producing proteoglycans that limit nerve regeneration, "we're getting to know the molecules -- the players -- and what they do," Silver says.
Quantitative evaluation of the tendon cell density, thickness of the fibrocartilage zone and area of proteoglycan
The paper is titled "The proteoglycan bikunin has a defined sequence.
In our investigations we showed that - alongside the synthesis of Type II collagen - FORTIGEL(R) induces the increased production of aggrecan, a special proteoglycan which is of central importance to the cartilage function," explains Dr.
Laboratoires Serobiologiques (LS) has designed Dermican with a unique anti-aging action that targets the metabolism of a specific proteoglycan (lumican) to enhance skin firmness.
All tested compounds inhibited dose-dependently IL-1[beta]-induced proteoglycan release and nitric oxide production by cartilage, indicating cartilage protective activity.