proteinase

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Related to proteinases: peptidase, proteolytic enzymes, Proteases

endopeptidase

 [en″do-pep´tĭ-dās]
any peptidase that catalyzes the cleavage of internal bonds in a polypeptide or protein. Inhibition of the action of endopeptidases (proteases) in viruses causes formation of noninfectious particles; certain antiviral drugs work in this way (see protease inhibitors). Called also protease and proteinase.

en·do·pep·ti·dase

(en'dō-pep'ti-dās),
An enzyme that catalyzes the hydrolysis of a peptide chain at points well within the chain, not near either terminus; for example, pepsin, trypsin. Compare: exopeptidase.
Synonym(s): proteinase

proteinase

/pro·tein·ase/ (pro´tēn-ās″) endopeptidase.

proteinase

(prōt′n-ās′, -āz′, prō′tē-nās′, -nāz′)
n.
An endopeptidase, such as pepsin, trypsin, or papain.

proteinase

[prō′tē·inās]
Etymology: Gk, proteios, first rank, ase, enzyme suffix
a proteolytic enzyme that splits protein molecules at central linkages. Also called tryptase.

proteinase

see ENDOPEPTIDASE.

protease

; proteinase enzyme that breaks down/proteolyses protein

proteinase

any enzyme that catalyzes the splitting of interior peptide bonds in a protein; an endopeptidase.

proteinase resistant protein (prp)
a protein which resists digestion by proteinases; the amyloid fibrils in brain tissue of sheep affected with scrapie contain such a prp.
References in periodicals archive ?
There are many players in this over reaction, including an immune protein called TLR4, or toll-like receptor 4, and enzymes called proteinases in allergens.
Two wound-inducible soybean cysteine proteinase inhibitors have greater insect digestive s proteinase inhibitory activities than a constitutive homolog.
The bacteriocin production and proteinase activity of natural isolates of enterococci may be of interest to processors of dairy and meat-fermented products.
Thus, the meat tenderization process under high-pressure conditions probably involves proteasomes, in combination with other intramuscular proteinases.
Due to strict pH dependence for enzyme activity, lysosomal proteinases have been largely neglected as potential therapeutic proteins due to their inability to digest proteins outside the lysosomal compartment in the cell," said Gilbert Keller, PhD, Halozyme's Technical Leader in Dermatology.
Secreted aspartyl proteinases and interactions of Candida albicans with human endothelial cells.
Cells have well over 200 different proteinases that, either by themselves or as part of a larger proteolytic system composed of several enzymes, degrade proteins (see the accompanying table for a summary of these proteinases and systems).
This analysis also implies that active and self-inhibited forms of other aspartic proteinases can exist in solution helping to explain the results of kinetic studies of these enzymes.
The discovery that substrate cleavage by some proteinases was affected by the sequence of several residues in the substrate preceding the site of cleavage (7-11) opened the way to developing substrates that were relatively specific for assaying particular proteinases.
6]-dependent enzymes, proteinases in all four subclasses, phospholipases, kinases and transglutaminases, were among the drug targets encompassing numerous therapeutic areas, i.
Proteinases are enzymes that animals - insects in this instance - use to digest proteins.