protein-bound iodine


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iodine

 (I) [i´o-dīn]
a chemical element, atomic number 53, atomic weight 126.904. (See Appendix 6.) Iodine is essential in nutrition, being especially prevalent in the colloid of the thyroid gland. It is used in the treatment of hypothyroidism and as a topical antiseptic. Iodine is a frequent cause of poisoning (see iodism). Deficiency of iodine causes goiter. Since iodine salts are opaque to x-rays, they can be combined with other compounds and used as contrast media in diagnostic x-ray examinations of the gallbladder and kidneys.
iodine 123 a radioactive isotope of iodine having a half-life of 13.2 hours and emitting gamma rays and x-rays. It is used in diagnostic imaging and as radiation sources in radiation therapy. Symbol 123I.
iodine 125 a radioisotope of iodine having a half-life of 60.14 days and emitting gamma rays; used as a label in radioimmunoassays and other in vitro tests, and also for thyroid imaging. Symbol 125I.
iodine 131 a radioactive isotope of iodine having a half-life of 8.04 days and emitting beta particles and gamma rays. It is used as a tracer in diagnostic imaging and as a radiation source in radiation therapy. Symbol 131I.
protein-bound iodine a test of thyroid function; see also protein-bound iodine test.
radioactive iodine radioiodine.
iodine solution a transparent, reddish brown liquid, each 100 ml of which contains 1.8 to 2.2 g of iodine and 2.1 to 2.6 g of sodium iodide; a local antiinfective agent.
strong iodine solution Lugol's solution.

pro·tein-bound i·o·dine (PBI),

thyroid hormone in its circulating form, consisting of one or more of the iodothyronines bound to one or more of the serum proteins.

protein-bound iodine

Abbreviation: PBI
Iodine that is attached to serum protein. In the past, thyroid function was tested with a serum measurement of PBI.
See also: iodine

iodine

a chemical element, atomic number 53, atomic weight 126.904, symbol I. See Table 6. Iodine is essential in nutrition, being especially prevalent in the colloid of the thyroid gland. It is used in the treatment of hypothyroidism and as a topical antiseptic. Iodine is a frequent cause of poisoning. See also iodism.

iodine-125
a radioisotope of iodine having a half-life of 60 days and a principal gamma-ray photon energy of 28 keV; used as a label in radioimmunoassays and other in vitro tests, and also for thyroid imaging. Symbol 125I.
123iodine-metaiodobenzylguanidine
a radioisotope which concentrates in chromaffin cells; used in diagnostic scintigraphy, e.g. in cases of pheochromocytoma.
iodine-131
a radioisotope of iodine having a half-life of 8.1 days and a principal gamma-ray photon energy of 364 keV; used in treatment of hyperthyroidism and carcinoma of the thyroid, in thyroid function testing, and in imaging of the thyroid gland and other organs. Symbol 131I.
iodine deficiency
may occur in all species under certain conditions; in dogs and cats, a factor in all-meat diets. See also goiter.
iodine contrast agents
iodine salts are opaque to x-rays; therefore they can be combined with other compounds and used as contrast media in diagnostic x-ray examinations.
iodine nutritional deficiency
is characterized by goiter, neonatal mortality and alopecia.
iodine poisoning
occurs usually due to accidental overdosing. It causes lacrimation, anorexia, coughing due to bronchopneumonia, and a heavy dandruff. Paradoxically, iodine excess may result in thyroid hyperplasia and goiter, especially in the young.
protein-bound iodine
a test of thyroid function. See also protein-bound iodine (PBI) test.
radioactive iodine
see iodine-125, iodine-131 (above).
iodine residues in milk
careless use of iodine-based teat dips results in unacceptable residues of iodine in milk.
iodine solution
contains 2% free iodine and 2.4% sodium iodide in an aqueous solution.
iodine solution (strong)
contains 5% free iodine and 10% potassium iodide in an aqueous solution.
tamed iodine
iodine trapping
the selective absorption of iodine from the circulation by the thyroid gland.
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