protein truncation test

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protein truncation test,

a method for detection of one or more translation termination mutations in a gene that cause a truncated, usually inactive, protein to be synthesized. The appropriate genomic DNA or mRNA is isolated, amplified by polymerase chain reaction, and used as a template for in vitro transcription and translation. The size of the resulting protein is compared with that of a wild type protein by means of SDS-polyacrylamide gel electrophoresis.

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No references found			As the list of known heritable gene disorders grows, advanced research techniques such as PCR reverse dot blot and the protein truncation test are bolstering the role of molecular biology in genetic testing and counseling. Molecular diagnosis of inherited disease by Rohlfs, Elizabeth M.; Silverman, Lawrence M. / Medical Laboratory Observer			protective laryngeal reflex Protective Posture Gear protector proteid protein protein antibiotic protein C protein C deficiency protein C-protein S test protein calorie malnutrition protein catabolic rate protein channel Protein Components Test protein diet Protein Drink protein electrophoresis protein hydrolysate protein hydrolysate injection protein kinase Protein Malnutrition protein metabolism protein restriction protein S protein S deficiency protein sensitization protein truncation test protein-bound protein-bound iodine protein-bound iodine test protein-energy malnutrition protein-losing enteropathy protein-sparing proteinaceous proteinase proteinemia proteinoid proteinosis proteins proteinuria Proteinuric Syndrome Proteles cristatus proteo- Proteocephalus proteoclastic proteoglycan proteoglycans proteolipid proteolysis proteolytic proteolytic enzymes proteome			protein shock protein shock Protein Society Protein Sparing Modified Fast Protein Specific Antigen protein specificity protein specificity protein specificity Protein Stability-Function Relations Protein Structure and Function Protein Structure and Interaction Analyzer Protein Structure Initiative Protein structure prediction Protein structure, quaternary Protein structure, secondary Protein structure, secondary Protein structure, tertiary Protein structure, tertiary Protein Subcellular Location Image Database Protein subunit Protein subunit Protein Supplements Protein Supplements Protein Supplements Protein Synthesis Inhibition Protein therapy Protein to Creatinine Ratio Protein to Energy Ratio Protein Transduction Domain protein translocator protein truncation test Protein Turn Over Rate Protein Tyrosine Kinase Protein Tyrosine Kinase 2 Beta Protein Tyrosine Kinase 6 Protein Tyrosine Kinase 7 Protein Tyrosine Kinase 9 Protein Tyrosine Kinase Inhibitor Protein Tyrosine Kinase Receptor Protein tyrosine phosphatase Protein Tyrosine Phosphatase 1 Protein Tyrosine Phosphatase Epsilon Protein Tyrosine Phosphatase Like Protein Protein Tyrosine Phosphatase Receptor Protein Tyrosine Phosphatase Receptor Omicron Protein Tyrosine Phosphatase Receptor Q Protein Tyrosine Phosphatase Receptor Type O Protein Tyrosine Phosphatase Receptor type R Protein Tyrosine Phosphatase, Receptor Type, Gamma Protein Tyrosine Phosphatase, Receptor Type, T Protein Tyrosine Phosphatase-Like B Protein tyrosine-kinase Protein Z-dependent protease inhibitor Protein Zero-Related Protein, Conjugated Protein, Conjugated Protein, Conjugated

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