protein profiling

protein profiling

The detection of the character and quantity of specific sets of proteins in blood or other specimens. Protein profiling has been used as a means of diagnosing specific illnesses, esp. cancers or infectious diseases known to release unique protein patterns into serum. Protein profiling may be used as a means of screening for cancer recurrence in previously treated patients or in patients with multiple risk factors for an illness. It may also aid in the crafting of therapies, e.g., by demonstrating that a particular disease is susceptible to a specific drug therapy. Synonym: protein correlation profiling; serum protein profiling; serum protein-expression profiling
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Founded in 1999 and based in New Haven, Connecticut, Agilix developed the PROT (Isobaric Protein Label) multiplex protein labeling platform technology for in vivo and in vitro protein profiling.
Merrick points to protein profiling as an important use of proteomics in toxicology (toxicoproteomics).
The company currently offers 10 unique signal transduction protein profiling services for tracking over 180 protein kinases, 130 known phosphorylation site targets of kinases and 110 other signalling proteins that regulate cell proliferation, stress and death.
The Tegal etch tool will be used by Zyomyx to create Protein Profiling Biochips.
These capabilities allow both quantitative and qualitative analysis to be performed using techniques such as protein profiling, SILAC and iTRAQ with both CID and ETD fragmentation.
The project includes a publically available portal for researchers in life sciences and provides access to protein profiling data in 46 normal tissues, 20 cancer tissues and 46 cell lines on a subcellular level.
Next, multidimensional protein profiling - a more complex and in-depth proteomics analysis - was used to measure cytokines that have been associated with DHF in other studies.
The book begins with microarray data analysis, machine learning techniques, and mass-spectrometry-based protein profiling.
Caprioli's group is nearing completion of a similar study of brain tumors with similar results in terms of the power of tissue protein profiling for prognostication.
The company's initial product offerings include the Protein Profiling Biochip System and the Human Cytokine Biochip.
Zymoyx launched its Protein Profiling Biochip System, consisting of validated biochips, an Assay 1200 automated workstation, the Scanner 100 biochip reader and data analysis software.