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protein kinase/pro·tein ki·nase/ (pro´tēn ki´nās) an enzyme that catalyzes the phosphorylation of serine, threonine, or tyrosine groups in enzymes or other proteins, using ATP as a phosphate donor.
Any of a group of kinases that phosphorylate the amino acids serine, threonine, and tyrosine in certain proteins, that regulate essential aspects of cell growth and movement, and that can cause cancer and other diseases when dysfunctional.
protein kinase (PKA)
a protein that catalyzes the transfer of a phosphate group from adenosine triphosphate to produce a phosphoprotein.
protein kinaseThis name was officially retired in 2005; however, although the term is nonspecific, it is still in common use. It is now formally divided into:
• EC 184.108.40.206, non-specific serine/threonine protein kinase;
• EC 220.127.116.11, Fas-activated serine/threonine kinase;
• EC 18.104.22.168, Goodpasture antigen-binding protein kinase;
• EC 22.214.171.124, IκB kinase;
• EC 126.96.36.199, cAMP-dependent protein kinase;
• EC 188.8.131.52, cGMP-dependent protein kinase;
• EC 184.108.40.206, protein kinase C;
• EC 220.127.116.11, polo kinase;
• EC 18.104.22.168, cyclin-dependent kinase;
• EC 22.214.171.124, mitogen-activated protein kinase;
• EC 126.96.36.199, mitogen-activated protein kinase kinase kinase;
• EC 188.8.131.52, receptor protein serine/threonine kinase; and
• EC 184.108.40.206, dual-specificity kinase.