S100A3

(redirected from protein S100-A3)

S100A3

A gene on chromosome 1q21 that encodes a member of the S100 family of proteins, which have 2 EF-hand calcium-binding motifs. S100 proteins are localised in the cytoplasm and/or nucleus of a wide range of cells; they are involved in regulating cell cycle progression and differentiation and other intracellular activities. The S100A3-encoded protein is highly expressed in skin and may be involved in calcium-dependent differentiation of skin and hair shaft.