protein 4.1

(redirected from protein 41)

pro·tein 4.1

a peripheral protein that binds tightly to spectrin in the red blood cell membrane; it also binds to certain glycophorins and helps determine the shape and flexibility of the red blood cell.


A gene on chromosome 1p33-p32 that encodes protein 4.1, which, with spectrin and actin, constitutes the red cell membrane cytoskeletal network. This network plays a critical role in red cell shape and deformability.

Molecular pathology
EPB41 mutations cause elliptocytosis type 1.
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Laboratory results were as follows: erythrocyte sedimentation rate 65 mm/hour, C-reactive protein 41 mg/L, negative results for rheumatoid factor, anti-cyclic citrullinated peptide antibodies, antinuclear antibodies, ribonucleoprotein antibodies, anti-Sjogren's syndrome A, anti-Sjogren's syndrome B, anti-systemic sclerosis topoisomerase I, anti-jol, anti-double stranded deoxyribonucleic acid and anti-histone antibodies.
Figure 15: Consumers pay more attention to fat, sugar and carbohydrate intake than they do to protein 41
OTCBB:LXXN) today announced laboratory confirmation that the gene for the ebaf protein actually codes for a precursor protein 41 kD (kilo Daltons) in size.