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protamine sulfate |
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protamine sulfate
[prō′təmēn] a heparin antagonist derived from fish sperm. indication It is prescribed to diminish or reverse the anticoagulant effect of heparin, particularly in cases of heparin overdosage. contraindications Pregnancy, allergy to fish, or known hypersensitivity to this drug prohibits its use. adverse effects Among the more serious adverse effects are hypotension, dyspnea, and bradycardia. Dosage greater than needed to neutralize heparin causes the toxic and anticoagulant effects of protamine. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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