prostanoids

pros·ta·no·ids

(pros'tă-nō'ids),
Derivatives of prostanoic acid; for example, prostaglandins, thromboxanes, etc.

prostanoids

(pros-ta-noyds)
The name of the end products of the cyclooxygenase pathway of the metabolism of arachidonic acid. These are prostaglandins and thromboxanes.
See: eicosanoid; prostaglandin; thromboxane A2
References in periodicals archive ?
It modulates the expression of proinflammatory genes transcription for cytokines, growth factors, adhesion molecules, nitric oxide, prostanoids and autacoids.
Based on the known mechanisms, 3 classes of drugs have been used to treat pediatric pulmonary hypertension (PH): prostanoids (e.
Prostanoids are cyclic and oxygenated metabolites comprised of [omega]-3 and [omega]-6 20-carbon essential fatty acids, and they have a broad range of biological activities.
Their primary influence is on the cyclooxygenase or COX pathway, in which chemical reactions create prostanoids, a family of lipid mediators that cause pain and inflammation in nerve endings and in the spinal cord.
The body's inflammatory response involves an enzyme, cyclooxygenase (COX), that helps form prostanoids, key components in the development of inflammation.
Sodium tungstate and vanadyl sulfate effects on blood pressure and vascular prostanoids production in fructose-overloaded rats.
2+]/NFAT cascade in cardiomyocytes, leading to cyclooxygenase type 2 (COX-2) induction and increased release of prostanoids and prohypertrophic peptides.
A disruption in immune tolerance, results in excitement that may involve multiple pathways such as production of cytotoxic antibodies, activation of T-cells (Feghali and Wright, 1997; Barton, 1999) cytokines and prostanoids (prostaglandins, prostacyclin, and thromboxane) production from arachidonic acid during chronic inflammation.
In addition, cytokines and prostanoids, as well as matrix metalloproteinases activated through the host response, may stimulate damage to connective tissue and bone and shape the clinical presentation of disease.
Cyclooxygenase- (COX-) 1 and COX-2 are the two isoforms of cyclooxygenase, both of which catalyze the transformation of arachidonic acid to prostanoids [4-6].