prostaglandins


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prostaglandins

A group of unsaturated fatty acid mediators occurring throughout the tissues and body fluids. They are generated from cell membrane ARACHIDONIC ACID by the action of phospholipase A2 and function as hormones. They have many different actions. They cause constriction or widening of arteries, they stimulate pain nerve endings, they promote or inhibit aggregation of blood PLATELETS and hence influence blood clotting, they induce abortion, reduce stomach acid secretion and relieve asthma. They can both stimulate and inhibit immune responses. Some painkilling drugs, such as aspirin, act by preventing the release of prostaglandins from injured tissue.

prostaglandins

a group of lipid substances that exert a wide range of stimulatory effects on the body, the most important of which is the enhancement of the effects of CYCLIC AMP. Prostaglandins are derived from many tissues including the prostate gland (or can be made synthetically), and have been used in the induction of labour and abortion.

Prostaglandins

Prostaglandins are produced by the body and are responsible for inflammation features, such as swelling, pain, stiffness, redness and warmth.

prostaglandins

vaso- and myoactive substances that trigger and perpetuate pain and inflammation

prostaglandins (prˈ·st·glanˑ·dinz),

n.pl a family of lipid compounds found in various tissues, associated with muscular contraction and the inflammation response.
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Proptosis.

prostaglandins (pros´təglan´dinz),

n.pl a group of potent hormonelike substances that produce a wide range of body responses such as changing capillary permeability, smooth muscle tone, clumping of platelets, and endocrine and exocrine functions. They are involved in the pain process of inflammation.
References in periodicals archive ?
The selectivity for prostaglandin production is determined by the terminal prostaglandin synthase enzyme present in cells expressing COX-1 and COX-2.
While these studies looked at AGA in men, the researchers noted that prostaglandins may represent a common pathway shared by both men and women with AGA.
It is thought that the Pill interferes in some way with the production of prostaglandins, thereby making muscle spasms less likely.
This effect most likely occurs through the inhibition of prostaglandin and subsequent inhibition of estrogen biosynthesis.
Women in the intra-amniotic prostaglandin group had significantly more episodes of vomiting requiring treatment than those in the oral misoprostol group (on average, 0.
Two prostaglandins used early on in conjunction with RU486 in France, gemeprost and sulprostone, were largely abandoned after one of the four women suffering heart attacks died in 1992.
Long before prostaglandins (PGs) were detected in plants they had been discovered in mammals (humans).
The notion that anti-inflammatory agents might prevent tumors arose in the 1970s with the observation that colon tumors produced unusually high concentrations of prostaglandins.
He was one of three recipients who shared the 1982 Nobel Prize in medicine for their work on prostaglandins, specifically the discovery of prostanoids and leukotrienes.
However, at the present time, no one knows whether or how these prostaglandins help breast cancers grow.
Prostaglandins are grouped as body's master hormones, and percussor prostaglandin balancers as a dietary supplement for obesity in overweight diabetic women is in development.