prostaglandin synthase

prostaglandin synthase

/pros·ta·glan·din syn·thase/ (sin´thās) an enzyme catalyzing the initial steps in the synthesis of prostaglandins from arachidonic acid; it comprises the component activities cyclooxygenase, catalyzing cyclization and oxidation reactions, and peroxidase, catalyzing a reduction reaction.
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2], which in turn is converted by terminal prostaglandin synthase enzymes to specific classes of prostaglandins.
The selectivity for prostaglandin production is determined by the terminal prostaglandin synthase enzyme present in cells expressing COX-1 and COX-2.

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