epoprostenol(redirected from prostaglandin I2)
Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
A potent natural inhibitor of platelet aggregation and a powerful vasodilator.
epoprostenol/ep·o·pro·sten·ol/ (e″po-pros´tĕ-nol) name for prostacyclin when used pharmaceutically; used in the form of the sodium salt as an inhibitor of platelet aggregation when blood contacts nonbiological systems, a pulmonary antihypertensive, and a vasodilator.
name for prostacyclin when used pharmaceutically. It is used in the form of the sodium salt as an inhibitor of platelet aggregation for blood contacting nonbiological systems, as in renal dialysis; as a pulmonary antihypertensive; and as a vasodilator.
BeraprostAn oral prostacyclin PGI2 analogue with vasodilator, antiplatelet, and cytoprotective effects, used to manage pulmonary arterial hypertension. Beraprost improves exercise capacity and symptoms in NYHA-functional class-II and -III patients with PAH and, in particular, in those with primary pulmonary hypertension.
Headache, facial flushing, vasodilation.
epoprostenolProstacyclin. A powerful inhibitor of clumping of blood platelets and thus of blood clotting. It is used with heart-lung (cardiopulmonary bypass) machines and artificial kidneys (dialysis machines) to preserve the platelets in the blood being pumped through them. Epoprostenol also widens (dilates) arteries. A brand name is Flotan.