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prostacyclin

   Also found in: Dictionary/thesaurus, Acronyms, Wikipedia, Hutchinson 0.03 sec.
prostacyclin /pros·ta·cy·clin/ (pros″tah-si´klin) a prostaglandin, PGI2, synthesized by endothelial cells lining the cardiovascular system; it is a potent vasodilator and inhibitor of platelet aggregation. It is used pharmaceutically as epoprostenol.
pros·ta·cy·clin (prst-skln)
n.
A prostaglandin produced in the walls of blood vessels that acts as a vasodilator and inhibits platelet aggregation.

prostacyclin (PGI2)
[pros′təsī′klin]
a prostaglandin. It is a biologically active product of arachidonic acid metabolism in human vascular walls and a potent inhibitor of platelet aggregation. It inhibits the vasoconstrictor effect of angiotensin and stimulates renin release and has been used to treat pulmonary hypertension.

prostacyclin
a metabolite of arachidonic acid formed by prostaglandin endoperoxides in the walls of arteries and veins; it is a potent vasodilator and an inhibitor of platelet aggregation. The exogenous form is called epoprostenol.


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