PCSK5

(redirected from proprotein convertase subtilisin/kexin type 5)

PCSK5

A gene on chromosome 9q21.3 that encodes a broadly active endoprotease of the peptidase S8 family involved in the constitutive and regulated secretory pathway. It cleaves the RX(K/R)R consensus motif and plays an essential role in establishing pregnancy through the proteolytic activation of key factors, such as BMP2 and CALD1.