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proprotein

   Also found in: Wikipedia 0.01 sec.
proprotein /pro·pro·tein/ (pro-pro´tēn) a protein that is cleaved to form a smaller protein, e.g., proinsulin, the precursor of insulin.
proprotein [pro-pro´tēn]
a protein precursor that is cleaved to form an active protein, e.g., proinsulin, the precursor of insulin.

proprotein
a protein which is cleaved to form a smaller protein, e.g. proinsulin, the precursor of insulin.


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PCSK9 proprotein convertase promotes the degradation of the receptor responsible for eliminating LDL-cholesterol particles.
Sucic, University of Michigan--Flint, Department of Biology, Flint, MI 48502 Paired Basic Amino Acid Cleaving Enzyme 4 (PACE4) is a eukaryotic endoprotease in the subtilisin-like proprotein convertase (SPC) family.
Alnylam's ALN-PCS program is focused on using RNAi therapeutics targeting proprotein convertase subtilisin/kexin type 9, or PCSK9, as a novel strategy for reducing LDL (or "bad") cholesterol.
 
 
 
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