propionyl CoA

propionyl CoA

activated intermediate in the utilization of the volatile fatty acid, propionic acid; or end product of the beta-oxidation of odd-carbon chain fatty acids.
References in periodicals archive ?
The hyperammonemia observed in methylmalonic acidemia is thought to arise because accumulated propionyl CoA interferes with formation of N-acetylglutamate, an obligatory activator of carbamyl phosphate synthase, the initial step in urea synthesis (4).
The process starts with the metabolism of various compounds in the mitochondrion to form propionyl CoA (Figure 1).