prophylactic oophorectomy

prophylactic oophorectomy

Oncology The excision of the ovaries in a ♀ with a mutation in BRCA1 or BRCA2–associated with a 5–60% lifetime risk of ovarian CA–normal risk is 1.5%–undergoes prophylactic removal of ovaries. See Bilateral mastectomy, Prophylactic mastectomy.
References in periodicals archive ?
Occult carcinoma in prophylactic oophorectomy specimens: prevalence and association with BRCA germline mutation status.
The Role of prophylactic oophorectomy in the management of hereditary breast & ovarian cancer syndrome, Hysterectomy, Dr.
Effect of short-term hormone replacement therapy on breast cancer risk reduction after bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group.
Elkadry suggested that there may be an accelerated trend toward prophylactic oophorectomy.
Options for women to consider include "intensive surveillance for breast cancer primarily, consideration of medications to reduce the risk of breast cancer, and either prophylactic mastectomy or prophylactic oophorectomy.
The potential for loss of ability to respond sexually is a very important consideration for women who are being advised to do prophylactic oophorectomy," said Dr.
Two babies and 4 years later, Judith is in therapy again, contemplating bilateral prophylactic oophorectomy (BPO) that will push her into surgical menopause and significantly reduce her risk of both ovarian and breast cancer.
It is interesting that some of these patients underwent bilateral prophylactic oophorectomy (BPO) and multivariate Cox analysis suggested that this led to a significant benefit in overall survival at 5 years.
We spoke about my sister's case and he calmly advised me to have my ovaries removed--a procedure known as a prophylactic oophorectomy.
In women who have the BRCA1 or BRCA genes, we recommend prophylactic oophorectomy," says Farr Nezhat, MD, professor of Obstetrics, Gynecology, and Reproductive Medicine at Mount Sinai Medical Center.