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prophylactic antibiotic therapy

   Also found in: Dictionary/thesaurus, Legal, Encyclopedia 0.01 sec.
prophylactic
1. tending to ward off disease; pertaining to prophylaxis.
2. an agent that tends to ward off disease.

prophylactic antibiotic therapy
treatment with antibiotics, beginning just before a surgical procedure, to minimize or prevent development of infection. See also perioperative.
prophylactic vaccination
vaccination carried out in expectation of the occurrence of the disease.

prophylactic antibiotic therapy
Administration of antimicrobials in absence of a known infection, a standard practice to ↓ risk of surgical wound infection Common surgical wound pathogens Staphylococcus aureus, Bacteroides fragilis, Enterobacter cloacae; most commonly used are 3rd-generation cephalosporins; PAT is best if administered 2 hrs presurgery


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