prophylactic antibiotic therapy

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prophylactic antibiotic therapy

Administration of antimicrobials in absence of a known infection, a standard practice to ↓ risk of surgical wound infection Common surgical wound pathogens Staphylococcus aureus, Bacteroides fragilis, Enterobacter cloacae; most commonly used are 3rd-generation cephalosporins; PAT is best if administered 2 hrs presurgery


1. tending to ward off disease; pertaining to prophylaxis.
2. an agent that tends to ward off disease.

prophylactic antibiotic therapy
treatment with antibiotics, beginning just before a surgical procedure, to minimize or prevent development of infection. See also perioperative.
prophylactic vaccination
vaccination carried out in expectation of the occurrence of the disease.