prophage


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Related to prophage: lysogen, Lysogenic conversion, virulent phage

prophage

 [pro´fāj]
the latent stage of a bacteriophage in a lysogenic bacterium, in which the viral genome becomes inserted into a specific portion of the host chromosome and is duplicated into each cell generation.

pro·bac·te·ri·o·phage

(prō'bak-tē'rē-ō-fāj'),
The stage of a temperate bacteriophage in which the genome is incorporated in the genetic apparatus of the bacterial host.
Synonym(s): prophage

prophage

/pro·phage/ (pro´fāj) the latent stage of a phage in a lysogenic bacterium, in which the viral genome becomes inserted into a specific portion of the host chromosome and is duplicated in each cell generation.

prophage

(prō′fāj′)
n.
The latent form of a bacteriophage in which the viral genes are incorporated into the bacterial chromosomes without causing disruption of the bacterial cell.

pro·bac·te·ri·o·phage

(prō'bak-tēr'ē-ō-fāj)
The stage of a temperate bacteriophage in which the genome is incorporated into the genetic apparatus of the bacterial host.
Synonym(s): prophage.

prophage

the DNA of a BACTERIOPHAGE that is repressed (see GENE REPRESSION) for LYTIC functions and that is maintained in the host bacterium in a stable state. The prophage may be integrated into the DNA of its bacterial host and may be replicated along with the host DNA, as is the case for BACTERIOPHAGE LAMBDA, or may be maintained as EXTRACHROMOSOMAL DNA, as is the case for bacteriophage P1. Prophage DNA may be carried between GENERATIONS (2) in this state and no phage particles are produced. However, the prophage normally retains the ability to direct a lytic cycle, by the activation of genes for lytic development. Upon INDUCTION (3), progeny phages are produced and released from the host. see LYSOGENY.

prophage

the latent stage of a bacteriophage in a lysogenic bacterium, in which the viral genome becomes inserted usually at a specific location within the host chromosome and is duplicated into each cell generation.
References in periodicals archive ?
Importantly, genomic data suggested that the high virulence of that strain was due to acquisition of a prophage encoding Shiga toxin 2, a distinct set of virulence factors and antibiotic-resistance genes.
The Prophage Series G vaccines (HSPPC-96; vitespen) are being studied in two different settings of glioma: newly diagnosed and recurrent disease.
cholerae classical and El Tor biotypes co-existed suggesting the horizontal CTX prophage exchange between strains of the two principal biotypes in order for the infecting strains to be more adapted to the host hostile intestinal environment (15) which conformed to the more severe cholera symptoms in the afflicted hosts in the recent years (3,22,24).
Key Words: Bacteriophage (phage) P1, c1, lysogen, prophage.
These CT genes are carried by a prophage designated CTX[PHI] that forms filamentous non-lytic particles (14).
The volume opens with a section on the general background of phage biology, containing articles on phage and the early development of molecular biology, classification of bacteriophages, prophage genomics, comparative phage genomics, and phage ecology.
Induction of prophage [lambda] by dauno-rubicin and derivatives: correlation with antineoplastic activity.
Elimination of all prophage remnants eliminates cell lysis problems during production.
Additionally, we analyzed DT loci of both isolates and found that the DT gene is encoded by a toxigenic prophage, which is almost identical to the toxigenic phage of C.
cholerae, cholera toxin, is encoded in the genome of an integrated prophage CTX[PHI] (11,12).
Papers giving general information include the history of phage research and therapy, phage biology, bacteriophage evolution and the role of phages in host evolution, phage ecology and bacteria pathogenesis, phage lysis, and lysogeny, prophage induction and lysogenic conversion.
Thus, although lead seemed to be negative in an assay detecting mutation induction in bacteria (22), positive results were obtained in an assay detecting induction of [Lambda] prophage in E.