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The stage of a temperate bacteriophage in which the genome is incorporated in the genetic apparatus of the bacterial host.
prophage/pro·phage/ (pro´fāj) the latent stage of a phage in a lysogenic bacterium, in which the viral genome becomes inserted into a specific portion of the host chromosome and is duplicated in each cell generation.
The latent form of a bacteriophage in which the viral genes are incorporated into the bacterial chromosomes without causing disruption of the bacterial cell.
The stage of a temperate bacteriophage in which the genome is incorporated into the genetic apparatus of the bacterial host.
prophagethe DNA of a BACTERIOPHAGE that is repressed (see GENE REPRESSION) for LYTIC functions and that is maintained in the host bacterium in a stable state. The prophage may be integrated into the DNA of its bacterial host and may be replicated along with the host DNA, as is the case for BACTERIOPHAGE LAMBDA, or may be maintained as EXTRACHROMOSOMAL DNA, as is the case for bacteriophage P1. Prophage DNA may be carried between GENERATIONS (2) in this state and no phage particles are produced. However, the prophage normally retains the ability to direct a lytic cycle, by the activation of genes for lytic development. Upon INDUCTION (3), progeny phages are produced and released from the host. see LYSOGENY.
the latent stage of a bacteriophage in a lysogenic bacterium, in which the viral genome becomes inserted usually at a specific location within the host chromosome and is duplicated into each cell generation.