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properdin
(redirected from properdin pathway)

   Also found in: Dictionary/thesaurus, Legal, Encyclopedia, Wikipedia 0.01 sec.
properdin /pro·per·din/ (pro´per-din) factor P; a nonimmunoglobulin gamma globulin component of the alternative pathway of complement activation.
pro·per·din (pr-pûrdn)
n.
A natural protein in human blood serum that participates in the body's immune response by working in conjunction with the complement system.

properdin [pro´per-din]
a protein of the alternative complement pathway, augmenting complement activation. Called also factor P.

properdin
a normal, relatively heat-labile, nonantibody serum protein (a euglobulin) that, in the presence of complement component C3 and magnesium ions, is involved in the alternative complement pathway, and acts nonspecifically against gram-negative bacteria and viruses and plays a role in lysis of erythrocytes. It may act in conjunction with complement-fixing antibody.

properdin pathway
alternative complement pathway.


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Fearon DT, Ruddy S, Schur PH, et al: Activation of the properdin pathway of complement in patients with gram negative bacteremia.
 
 
 
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