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   Also found in: Wikipedia 0.01 sec.
proof reading
3'?5' exonuclease activity of DNA polymerase that results in the removal of erroneously incorporated nucleotides during DNA replication; responsible for the very high fidelity (>106) of polymerase.

proof reading site
a distinct site of aminoacyl-tRNA synthetases that preferentially recognizes and hydrolyzes mis-acylated tRNA.

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