promyelocyte


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promyelocyte

 [pro-mi´ĕ-lo-sīt″]
a precursor in the granulocytic series, intermediate between myeloblast and myelocyte, containing a few undifferentiated cytoplasmic granules.

pro·my·e·lo·cyte

(prō-mī'ĕ-lō-sīt'),
1. The developmental stage of a granular leukocyte between the myeloblast and myelocyte, when a few specific granules appear in addition to azurophilic ones.
2. A large uninuclear cell occurring in the circulating blood of persons with myelocytic leukemia.
[pro- + G. myelos, marrow, + kytos, cell]

promyelocyte

/pro·my·elo·cyte/ (-mi´il-o-sīt″) a precursor in the granulocytic series, intermediate between myeloblast and myelocyte, containing a few, as yet undifferentiated, cytoplasmic granules.promyelocyt´ic

promyelocyte

(prō-mī′ə-lə-sīt′)
n.
A cell containing a few granules that develops from a myeloblast and develops into a myelocyte during the differentiation of a granulocyte.

promyelocyte

[prōmī′ələsīt′]
precursor in the bone marrow myelocytic series that is intermediate in development between a myeloblast and a myelocyte. The cytoplasm contains prominent primary granules. Appears in peripheral blood in acute promyelocytic leukemia.
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Promyelocyte

pro·my·e·lo·cyte

(prō-mī'ĕ-lō-sīt)
1. The developmental stage of a granular leukocyte between the myeloblast and myelocyte, when a few specific granules appear in addition to azurophilic ones.
2. A large mononuclear cell of bone marrow representing an undifferentiated stage in the development of a granulocyte, between myeloblast and myelocyte; contains only a few undifferentiated cytoplasmic granules; rare in circulating blood except in myelocytic leukemias.
Synonym(s): premyelocyte, progranulocyte.
[pro- + G. myelos, marrow, + kytos, cell]

promyelocyte

(pro-mi'el-o-sit) [Gr. pro, before, + myelos, marrow, + kytos, cell]
1. A large mononuclear myeloid cell seen in the blood in leukemia.
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PROMYELOCYTE
2. Cell development between a myeloblast and a myelocyte, resembling a myeloblast. Synonym: progranulocyte See: illustration

promyelocyte

a precursor in the granulocytic series, intermediate between myeloblast and myelocyte, containing a few, as yet undifferentiated, cytoplasmic granules.
References in periodicals archive ?
Peripheral blood smear examination revealed conspicuous atypical lymphocytes and occasional promyelocytes (Figure 1A and 1B).
Both forms have promyelocytes with abnormal bilobed nuclei.
Retinoic acid and arsenic for treating acute promyelocyte leukemia.
These toxic granules are formed in the promyelocyte stage during neutrophil maturation, and contain antimicrobial substances.
1; q22); CBFB-MYH11 Acute promyelocyte leukemia with AML with maturation t(15; 17)(q22; q12); PML-RARA AML with t(9; 11)(p22; q23); Acute myelomonocytic leukemia MLLT3-KMT2A(MLL) AML with t(6; 9)(p23; q34); Acute monoblastic and monocytic DEK-NUP214 leukemia AML with inv(3)(q21q26.
Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocyte leukemia.
Although there is a general consensus concerning the criterion for identifying myeloblasts as agranular (type I) and granular blasts (types II and III), there is some disagreement concerning their definitions, and in practice it may be a matter of convention (subjective method) to differentiate them from the continuum of cells, such as determining whether the cell is a type III blast or a promyelocyte.
Stimulation of interleukin-S production by okadaic acid and vanadate in a human promyelocyte cell line, an HL-60 subline.
Antigen derived from human promyelocyte cell culture (HL-60) infected with the agent of HGE obtained from Westchester County, New York.
B, Bone marrow aspirate smear showing promyelocyte with bilobed nuclei, prominent nucleoli, and basophilic microgranular cytoplasm consistent with variant M3 morphology (case 3) (Wright-Giemsa, original magnifications X1000).
Antiproliferative activity of various Uncaria tomentosa preparations on HI-60 promyelocyte leukemia cells.
In this study we investigated the in vitro effects of resveratrol on the apoptotic cascades in human promyelocyte leukemia (HL-60) cells and first demonstrated that growth arrest- and DNA damage-induced gene 45 [alpha] (GADD45 [alpha]) and annexin A1 are involved in the apoptosis effects of resveratrol in these cells.