It has recently been reported that Japanese encephalitis virus (JEV) induces apoptosis in human promonocyte
cells through ASK1 activation.
In mammals, the monoblast-promonocyte
-monocyte differentiation occurs in bone marrow, with monoblasts and promonocytes
being detected in circulating blood only in specific pathological situations (Van Furth, 1989, 1992).
Effects of exogenous stress protein 70 on the functional properties of human promonocytes
through binding to cell surface and internalization.
Proliferation of promonocytes
, which can be stimulated by systemic inflammatory stimuli, leads to the increase of the number of circulating monocytes [29, 30].
used TLR4-stimulated THP1 human promonocytes
to mimic the adaptation stages of sepsis.
Cytochemical stains can be useful in APL because all forms of APL have strong staining for myeloperoxidase and Sudan black reactions, thus aiding in differentiation from AML with monocytic differentiation, which will typically be negative for myeloperoxidase or only have weak staining in promonocytes
Fifty-hertz Magnetic Fields Induce Free Radical Formation in Mouse Bone Marrow-derived Promonocytes
Pluripotential stem cell Myeloid Progenitors Myeloblast Monoblasts Marrow pool Mitotic Promelocytes Promonocytes
precursors Myelocytes Post-mitotic Metamyelocytes bands Blood and Neutrophils, Monocytes tissue eosinophils and function basophils Innate Macrophage immunologic function Progenitors Megakaryocyte Erythroid Lymphoid Marrow pool Mitotic Maturing Normoblasts Pre-B precursors megakaryocytes Post-mitotic Reticulocytes B lymphoblast Blood and Platelets Erythrocytes B tissue lymphocytes function and plasma cells Haemostasis Oxygen Adaptive transport immunologic function Progenitors Marrow pool Mitotic Pro-T precursors Post-mitotic Lymphoblast Blood and T-lymphocytes tissue and NK cells function Fig.
Blasts refer to myeloblasts, lymphoblasts, monoblasts, promonocytes
, and megakaryoblasts.
Nucleoli are usually absent or inconspicuous, but are more prominent in promonocytes
In 2 monocytic tumors, many of the nuclei were folded, consistent with promonocytes
Monoblasts and promonocytes
are included in the blast count as blast equivalents, while monocytes are excluded.