In perimenopausal age group (41-50 years), regarding histopathology of endometrium, in our study, proliferative endometrium
A significant number of cases showed disordered proliferative endometrium
in the 41-50 years age group.
Frequency and percentages were calculated for marital status, parity and morphological patterns, including proliferative endometrium
, secretory endometrium, endometrial hyperplasia with and without atypia and chronic endometritis.
An overall increase in the endometrial gland density, seen in most tissue present, with a lower volume percentage of stroma is the defining feature that separates disordered proliferative endometrium
This may be because cases which were reported as simple hyperplasia on D&C were completely removed during curettage leaving behind the basal endometrium only, which was then reported as proliferative endometrium
due to short time gap between the two procedures.
Cyclin D1 staining was evaluated in the glandular epithelium component and in the superficial epithelium component (except carcinoma cases) in each group of proliferative endometrium
, secretory endometrium, simple hyperplasia, complex hyperplasia, and adenocarcinoma.
In the above 40 age group, proliferative endometrium
The cases studied were divided into the following groups: proliferative endometrium
(n = 10), secretory endometrium (n = 10), endometrial hyperplasia (n = 40; 30 with no atypia, 10 with atypia), and carcinoma (n = 40; 20 endometrioid, 10 serous, and 10 clear cell).
In the above table, the proliferative endometrium
(85%) is the most common histopathology in perimenopausal abnormal bleeding and secretory endometrium is the second most common histopathology observed in the present study.
Using a monoclonal antibody, we detected CD117 expression in a high percentage of benign endometrium, with the most intense immunostaining in hyperplastic and proliferative endometrium
Histopathological Endometrial patterns were classified as Proliferative Endometrium
(PE), Secretory Endometrium (SE), Disordered Proliferative Pattern (DPP), Atrophic Endometrium (AE), Endometrial Polyp (EP), Chronic Endometritis (CE), Endometrial Hyperplasia (EH) and Endometrial Carcinoma (CA).
30, endometrial aspiration revealed proliferative endometrium