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prolactinoma

   Also found in: Wikipedia 0.01 sec.
prolactinoma /pro·lac·ti·no·ma/ (-lak″tĭ-no´mah) a pituitary adenoma that secretes prolactin.
prolactinoma [pro-lak″tĭ-no´mah]
a pituitary adenoma made up of lactotrophs that secretes excessive amounts of prolactin; this may delay puberty in either sex, cause galactorrhea-amenorrhea syndrome in women, or decrease libido and fertility in men. Called also prolactin cell or prolactin-secreting adenoma and lactotrope or lactotroph adenoma.

prolactinoma (prōˈ·lak·t·nōˑ·m),
n a noncancerous tumor of the pituitary gland, most often in women, that leads to excess production of prolactin, the hormone responsible for modulating lactation. Also called
secreting adenoma.

prolactinoma
Endocrinology A pituitary tumor more common in Pts < age 40 characterized by an excess secretion of prolactin–tumor size correlates with the prolactin level; smaller tumors, microprolactinomas, are more common in ♀; macroprolactinomas are more common in ♂ and associated with sexual dysfunction; women may become symptomatic while on OCs; menses may stop when OCs are discontinued; prolactinomas may grow during pregnancy and be diagnosed postdelivery. See Prolactin.


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2) Spinal epidural lipomatosis has been associated with Cushing's disease, Cushing's syndrome, hypothyroidism, pituitary prolactinoma, radiotherapy, obesity, and idiopathic causes.
PMS patients do not suffer from prolactinomas, but they hypersecrete prolactin in response to daily stressful events, which appears to stimulate the mammary gland and thereby cause mastodynia.
This is especially true of the diagnosis of prolactinoma because confirmatory imaging techniques are insensitive and nonspecific.
 
 
 
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