proinflammatory cytokine


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proinflammatory cytokine

Any of the circulating substances in the blood that deplete lean body mass in critical illness. They include several interleukins (IL-1, IL-6, and IL-8) and tumor necrosis factor.
See also: cytokine
References in periodicals archive ?
Despite all this, metal particle-induced proinflammatory cytokines such as IL-1[beta] and TNF-[alpha] are considered to be important factors for stimulating osteoclastogenesis.
Evidences show that proinflammatory cytokines, such as interleukin 6 (IL-6) and tumor necrosis factor-[alpha] (TNF-[alpha]), are the common causes of cachexia (Moldawer and Copeland 2000).
Alcoholic human brain also has more proinflammatory cytokines (He and Crews 2008).
Increased local or peripheral proinflammatory cytokine production, or both, will correlate with increased pain perception, stress, anxiety, and mood disturbance, as well as decreased quality of life in patients with a herniated lumbar disc.
In this study, we examined serum bio-markers in a cohort of fish consumers in Brazil to test associations between biomarkers of MeHg exposure and elevated ANA/ANoA and proinflammatory cytokines.
This thinking holds that epidural-related fever is the product of changes in thermoregulatory mechanisms, and that increases in proinflammatory cytokines such as interleukin-6 occur in normal pregnancy and labor.
Monocyte proinflammatory cytokine release is higher and glucocorticoid sensitivity is lower in middle aged men than in women independent of cardiovascular risk factors.
In mice lacking T cells, apple polyphenols were unable to protect against colitis or suppress proinflammatory cytokine expression, indicating apple polyphenols protect against colitis via the suppression of T cell activation and/or recruitment.
Physiological and biological responses were characterized by analysis of airway hyper-responsiveness (AHR), inflammatory cellular recruitment, total protein in bronchoalveolar lavage fluid, proinflammatory cytokine profiling, and ex vivo bronchial ring studies.
These results indicate that IBD is associated with a reduced ratio of T (reg) to Th17 cells in peripheral blood and is characterised by a proinflammatory cytokine microenvironment which supports the continued generation of Th17 cells.
13) have reported that proinflammatory cytokine IL-1a and IL-2 levels were significantly elevated in patients with ARF while TNF-[alpha] concentrations remained unchanged during different stages of the disease.