prohormone convertases

prohormone convertases

Enzymes that cleave prohormones to yield active hormones.
References in periodicals archive ?
Chromogranin A processing and secretion: specific role of endogenous and exogenous prohormone convertases in the regulated secretory pathway.
These granules contain pro-insulin-zinc hexamers which are further processed into mature insulin and C-peptide by the prohormone convertases PC1/3 and PC2.
However, other endoproteases, such as corin (9, 10), or prohormone convertases (11) may be involved in the posttranslational maturation of pro[BNP.
A well-established family of intracellular processing enzymes involved in prohormone maturation is the prohormone convertases (PCs).