progestin


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Related to progestin: progesterone

progestin

 [pro-jes´tin]
1. progestational agent.
2. a progestational agent secreted by the corpus luteum and stimulating release of proteolytic enzymes in preparation for ovulation and maturation of the endometrium.

pro·ges·tin

(prō-jes'tin),
1. A hormone of the corpus luteum.
2. Generic term for any substance, natural or synthetic, which effects some or all of the biologic changes produced by progesterone.
3. Synonym(s): gestagen
[pro- + gestation + -in]

progestin

/pro·ges·tin/ (-jes´tin) progestational agent.

progestin

(prō-jĕs′tĭn)
n.
Any of several synthetic progestational substances that mimic some or all of the actions of progesterone, used as contraceptives either alone or in combination with estrogen, and with estrogen in hormone replacement therapy.

progestin

[-jes′tin]
1 progesterone.
2 any of a group of hormones, natural or synthetic, secreted by the corpus luteum, placenta, or adrenal cortex that have a progesterone-like effect on the uterine endometrial lining to prepare it for implantation of the blastocyst.

pro·ges·tin

(prō-jes'tin)
1. A hormone of the corpus luteum.
2. Generic term for any substance, natural or synthetic, which effects some or all of the biologic changes produced by progesterone.
Compare: bioregulator
[pro- + gestation + -in]

Progestin

A synthetic or natural drug that acts on the uterine lining.

pro·ges·tin

(prō-jes'tin)
1. Hormone of corpus luteum.
2. Generic term for any substance, natural or synthetic, which effects some or all biologic changes produced by progesterone.
[pro- + gestation + -in]

progestin (prōjes´tin),

n a hormone that suppresses the release of luteinizing hormone and thereby inhibits the onset of menstruation. Synthetically produced progestin and estrogen are used in combination as an effective contraception.

progestin

originally, the crude hormone of the corpus luteum; it has since been isolated in pure form and is now known as progesterone. Certain synthetic and natural progestational agents are called progestins.
References in periodicals archive ?
The primary objective of the open-label, multi-center, single-arm, two-period Phase 2 study is to assess the antitumor activity of XBIO-101 in conjunction with progestin therapy as measured by overall disease control rate (ODCR).
Contraceptive vaginal ring: The vaginal ring (NuvaRing, Merck) has efficacy and side effects that are similar to those of the COCs, since it releases a combination of estrogen and progestin.
Estrogen with or without progestin decreased LDL and total cholesterol concentrations; increased HDL cholesterol and triglyceride concentrations; increased CRP and MMP-9 concentrations; decreased E-selectin concentrations; had no effect on IL-6 concentrations; increased plasmin-antiplasmin complex concentrations; decreased fibrinogen, plasminogen activator inhibitor 1 antigen, homocysteine, glucose, and insulin concentrations; and had no effect on D-dimer, factor VIII, prothrombin fragment 1.
The progestin in HT is included primarily to protect the uterine lining.
They found that breast cancer incidence was higher in estrogen plus progestin users than incidence in nonusers.
The overall 22% risk reduction that was found among users of estrogen plus progestin was nonsignificant, but there was a significant 36% reduced risk associated with sequential estrogen plus progestin regimens, and a significant 25% reduced risk associated with continuous combination regimens.
2), or a low dose of estrogen combined with a high dose of progestin (0.
In a study published in 2006 from the National Cancer Institute (NCI), five or more years of estrogen plus progestin use significantly increased the risk of ovarian cancer for women who had not had a hysterectomy.
The progestin in HT is included primarily to prevent buildup of the uterine lining.
The study included a subgroup of women from the estrogen alone and combined estrogen plus progestin arms of the Women's Health Initiative (WHI).
Progesterone is the proper name to signify identical-to-natural progesterone; progestin signifies non-bioidentical progesterone.
The Women's Health Initiative Study compared women who used estrogen and progestin to women who only used estrogen.

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