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ViaCyte's VC-01 product candidate, comprised of human PEC-01 pancreatic progenitor cells macroencapsulated in the Encaptra drug delivery system, has previously been demonstrated to regulate glucose levels in animal models, and is in an ongoing clinical trial designed to evaluate safety and efficacy in type 1 diabetes patients.
Upon receiving differentiation inducing signals, the progenitor cells lose expression of certain subunits of the exosome which leads to higher levels of GRHL3 protein.
Migration and division of progenitor cells populations in the periodontal ligament after wounding.
Effect of low doses of red wine and pure resveratrol on circulating endothelial progenitor cells.
Another source of inner ear progenitor cells are embryonic stem cells, which are derived from the inner cell mass of the mouse blastocyst (figure 3).
Specialty Pharmaceutical Companies: Neuronal Stem & Progenitor Cell Therapies
RGI has produced hES cell lines carrying genes for some of these hereditary diseases, and BioTime will use these cell lines to produce progenitor cells that will be offered to medical researchers.
Over the past few years, neuronal stem and progenitor cells have become of profound interest to the research community due to their potential to be used in drug discovery and delivery applications, as well as for tools of neural toxicology assessment.
Progenitor cells are further along in the differentiation process than HSCs.
BioTime has shipped inventory of six ACTCellerate[TM] progenitor cell lines to Millipore and plans to begin shipments of additional cell lines and ESpan[TM] cell growth media in the next several weeks.
With this new medium, reliable information on hematopoietic progenitor cell numbers in cord blood can be obtained much earlier than with standard 14-day assays.