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proestrogen

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proestrogen /pro·es·tro·gen/ (-es´trah-jen) a substance without estrogenic activity but able to be metabolized in the body to active estrogen.
pro·es·tro·gen (pr-str-jn)
n.
A precursor of estrogen that becomes an active hormone only after it has been metabolized.

proestrogen [pro-es´tro-jen]
a substance without estrogenic activity but which is metabolized in the body to active estrogen.

proestrogen
a substance without estrogenic activity but which is metabolized in the body to active estrogen.


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Further, methoxychlor, trans-stilbene, benzophenone, and benzo[a]pyrene are proestrogens that require metabolic activation by liver microsomal mixed-function oxidase in animals (Charles et al.
Further, methoxychlor is a proestrogen that requires demethylation by liver microsomal mixed function oxidase in animals before eliciting estrogenic activity (Kupfer and Bulger 1987; Stresser and Kupfer 1998).
Also, it is unclear to what degree proestrogens may, or may not, be activated to their estrogenic form in cultured cells.
 
 
 
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