product ion scan

product ion scan

In a multistage mass spectrometry (MS/MS) experiment, mass-selected precursor ions are induced to dissociate into product ions, which are then mass analysed by a second analyser.

The product ion scan is one of three common scans in the single-step MS/MS experiment, in which the first mass analyser is set at the mass of the selected precursor ion; the second mass analyser is then scanned from that mass downwards, resulting in a mass spectrum that contains signals for all the product ions formed from the selected precursor ion.
References in periodicals archive ?
1 Duo triple quadrupole mass spectrometer with EI with full scan, single quadrupole functionality, Secondary ion mass, selected reaction monitoring, multiple reaction monitoring, product ion scan, precursor ion scan, neutral loss scan, and simultaneous FS/SIM/SRM capabilities, with an extended capacity turbomolecular pump, electron impact ionization mode, and data system with fission (FPM).
Loss of the n-butyl moieties from the protonated molecular ion of MMA (m/z 231) yielded the fragment at m/z 119, which was not detected in the product ion scan of 20 [micro]mol/L succinic acid but became apparent at higher concentrations.
They include product ion scans to detect expected metabolites, as well as precursor ion scans and neutral loss scans to detect both expected and unexpected metabolite ions.

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