prodigiosin


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pro·dig·i·o·sin

(prō-dij'ē-ō'sin),
A red pigment synthesized by the bacterium Serratia marcescens; an antifungal agent.

prodigiosin

(prō-dĭj-ē-ō′sĭn)
A bright red pigmented chemical synthesized by Serratia marcescens and several other bacteria. It is cytotoxic and antibacterial.
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References in periodicals archive ?
Prodigiosin down-regulates survivin to facilitate paclitaxel sensitization in human breast carcinoma cell lines.
Prodigiosin is a tripyrrole first characterized from Serratia marcescens, which forms beautiful pillar box red colonies and S.
They produce prodigiosin at 25[degrees]C-28[degrees]C (77[degrees]F-82.
PRODIGIOSIN PIGMENT OF THE BACTERIUM SERRATIA MARCESCENS MAY FUNCTION TO SPILL EXCESS CELLULAR ENERGY.
Prodigiosin is a red pigment isolated from a few species of bacteria such as, Serratia, Pseudomonas and Streptomyces (11) and is a typical alkaloid compound produced as a secondary metabolite.
Prodigiosin is currently being evaluated for pre-clinical trials as a potential therapy for pancreatic cancer.
Prodigiosin synthesis on Tryptic Soy and Nutrient Agar supplemented with glucose, lactose, sucrose, or sorbitol was evaluated and colonies were subjected to growth on Triple Sugar Iron slants.
Serratia marcescens CR2B produces the red pigment prodigiosin characteristic of the species and probably adheres at least for that reason.
Aida has seven additional pipeline drugs in advanced stages of development: three gene therapy cancer drugs including patented Rh-Apo2l nearing the end of phase I trials, Prodigiosin for treating pancreatic cancer, Anti-CD86 monoclonal anti-body for the treatment of immunity-related diseases, Anti-CTLA-4 monoclonal anti-body for the treatment of tumors and stroke recovery medicine SYO2.
Serratia marcescens strain Nima expresses the red, intracellular pigment prodigiosin (5).
Aida Pharmaceuticals is developing a method to utilize the biochemical properties of Prodigiosin to create a non-invasive treatment for pancreatic cancer.