procollagen - definition of procollagen in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.

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procollagen /pro·col·la·gen/ (-kol´ah-jen) the precursor molecule of collagen, synthesized in the fibroblast, osteoblast, etc., and cleaved to form collagen extracellularly.

pro·col·la·gen (pr

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The soluble precursor of collagen possibly formed by fibroblasts in the process of collagen synthesis.

procollagen

the precursor of collagen, synthesized in osteoblasts and fibroblasts and subsequently converted to form collagen by procollagen peptidase.

procollagen N-peptidase

one of the enzymes involved in the conversion of procollagen to collagen. There is inadequate activity of this enzyme in osteogenesis imperfecta, dermatosparaxis.

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