procollagen


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Related to procollagen: tropocollagen

pro·col·la·gen

(prō-kol'ă-jen),
Soluble precursor of tropocollagen formed by fibroblasts and other cells in the process of collagen synthesis; unstable type III procollagen is associated with Ehlers-Danlos syndrome type IV.

procollagen

/pro·col·la·gen/ (-kol´ah-jen) the precursor molecule of collagen, synthesized in the fibroblast, osteoblast, etc., and cleaved to form collagen extracellularly.

pro·col·la·gen

(prō-kol'ă-jen)
Soluble precursor of collagen formed by fibroblasts and other cells in the process of collagen synthesis.

procollagen

the precursor of collagen, synthesized in osteoblasts and fibroblasts and subsequently converted to form collagen by procollagen peptidase.

procollagen N-peptidase
one of the enzymes involved in the conversion of procollagen to collagen. There is inadequate activity of this enzyme in osteogenesis imperfecta, dermatosparaxis.
References in periodicals archive ?
Structural organization and expression patterns of the human and mouse genes for the type I procollagen COOH-terminal proteinase enhancer protein.
Serum type III procollagen peptide and laminin (Lam-P1) detect alcoholic hepatitis in chronic alcohol abusers.
Biochemical indicators of bone formation were serum osteocalcin and aminoterminal propeptide of type I procollagen, and a marker for bone resorption was serum type I collagen carboxy-terminal telopeptide (CTx).
A subset of 520 women had biochemical markers of bone turnover (serum bone-specific alkaline phosphatase [BSAP], serum carboxy-terminal extension peptide of procollagen type 1 [PICP], urinary N-terminal telopeptide [NTX and urinary free deoxypyridinoline [DPD]) measured at baseline.
Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism.
Graham MF, Willey A, Adams J and Diegelmann RF: Corticosteroids increase procollagen gene expression, synthesis and secretion by human intestinal smooth muscle cells.
Revlon's Ultima 11 Procollagen Anti-Aging Complex Especially For Eyes is one of the new products that contains basic green tea extract.
The gene contains instructions to make Type II procollagen -- the precursor of Type II collagen, which is the major ingredient of joint-surface protective linings.
Increasing Procollagen III, an anti-wrinkle gene which promotes collagen in youthful skin, by 220 percent
For antidoping applications, serum concentrations of IGF-1 and the N-terminal propeptide of type III procollagen are used in combination to detect GH abuse (5-9).
Pravastatin therapy increases procollagen I N-terminal propeptide (PINP), a marker of bone formation in post-menopausal women.