procognitive

procognitive

(prō-kog-nĭ-tiv),
Denoting a drug which reduces delirium or disorientation.
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While not a measure of intellectual performance, a procognitive personality indicates an interest in abstract ideas, a drive to understand phenomena on a deep level and a willingness to expend considerable mental effort in solving problems (Ardelt, 2003).
and Europe is designed to determine the safety and efficacy of EVP-6124 in producing procognitive effects and improving the clinical condition of Alzheimer's disease patients.
Secondary receptor properties shared by some of these drugs may be sedating and may interfere with the drugs' procognitive actions Muscarinic cholinergic receptor antagonism seen with olanzapine and quetiapine may interfere with procholinergic actions on acetylcholine release related to improved cognition.
and Europe and was designed to determine the safety and efficacy of EVP-6124 in producing procognitive effects and improving the clinical condition of Alzheimer's disease patients.
The study is designed to determine the safety and efficacy of EVP-6124 in producing procognitive effects and improving executive function in schizophrenic patients who typically exhibit significant cognitive symptoms that impair normal functioning.
EHT 0202 is ExonHit's lead candidate in Alzheimer's disease and potentially first in a new class of disease modifying therapies which stimulate the -secretase pathway, thus enhancing the production of the procognitive and neuroprotective sAPP fragment of APP (Amyloid Precursor Protein).
EHT 0202 has the potential to be the first in a new class of disease modifying Alzheimer's disease therapies that stimulate the EaAAEeA-secretase pathway and may have neuroprotective and procognitive effects in addition to a symptomatic action.
EHT 0202 has a novel mechanism of action when compared to existing Alzheimer's disease therapeutics: it stimulates the alpha-secretase pathway, thus enhancing the production of the procognitive and neuroprotective sAPPalpha fragment of APP (Amyloid Precursor Protein).
EHT 0202 has a novel mechanism of action when compared to existing Alzheimer's disease therapeutics: it stimulates the -secretase pathway, thus enhancing the production of the procognitive and neuroprotective sAPP fragment of APP (Amyloid Precursor Protein).
On this occasion, ExonHit will reveal several posters and participate in an oral presentation, entitled "EHT 0202: A Neuroprotective And Procognitive Alpha-secretase Stimulator Targeted Towards Alzheimer Disease Therapy", lead by Matthew Pando, Ph.
There is a high unmet need for new Alzheimer treatments with procognitive and neuroprotective properties.
In light of the neuroprotective and procognitive effects demonstrated by EHT 0202 in preclinical studies, we believe that our drug candidate has the potential to modify the course of Alzheimer's disease and might open a new era in the treatment of this devastating disease," commented Dr.