procoagulant


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procoagulant

 [pro″co-ag´u-lant]
1. tending to promote coagulation.
2. a precursor of a natural substance necessary to coagulation of the blood.

procoagulant

/pro·co·ag·u·lant/ (-ko-ag´ūl-int)
1. tending to promote coagulation.
2. a precursor of a natural substance necessary to coagulation of the blood.

procoagulant

(prō′kō-ăg′yə-lənt)
n.
1. The precursor of any of various blood factors necessary for coagulation.
2. An agent that promotes the coagulation of blood.

procoagulant

[-kō·ag′yələnt]
an inactive coagulation protein that becomes activated during the coagulation process to form a serine protease or cofactor and produce a fibrin clot. Prothrombin is an example.

procoagulant

adjective Favoring coagulation; referring to activation of coagulation factors noun Any agent–eg, thrombin, factor Xa, which clots blood

procoagulant

1. tending to promote coagulation.
2. a precursor of a natural substance necessary to coagulation of the blood.
References in periodicals archive ?
Disorders of platelet procoagulant activity (Scott syndrome)
These MVs and remnant erythrocytes expressed phosphatidylserine (PS), an important mediator of procoagulant activation.
19) The first hypothesis suggests that CMV leads to a thrombotic micro-angiopathy by changing the nature of the endothelium from a anticoagulant to a procoagulant state.
Hypertriglyceridemia may present a procoagulant state since PAI-1 is increased in the presence of hypertriglyceridemia (Tholstrup et al.
Thus, lifelong increased concentrations of complement C3 may biologically be considered a procoagulant state, as also suggested by the present results.
Increased levels of procoagulants and reduced levels of inhibitors during pregnancy induce a hypercoagulable state, combined with a reactive fibrinolysis.
Monocyte-derived MVs are like endothelial-derived and erythrocyte-derived MVs significant sources of procoagulant activity due to their expression of tissue factor [40, 41], as well as of phosphatidylserine, a cofactor in the coagulation cascade [42].
Moreover, C5a can induce heparansulphate release from endothelial cell membranes so promoting a procoagulant activity and the membrane attack complex might mediate von Willebrand secretion and tissue factor expression.
Elevated levels of PGM may also inhibit the activated protein C (APC)- mediated inactivation of factor V Leiden leading to a procoagulant state (5).
Conclusions: CAD patients had a procoagulant state and presented with higher levels of hsCRP compared to the healthy individuals.
Visseren FL, Bouwman JJ, Bouter KP, Diepersloot RJ, de Groot PH, Erkelens DW: Procoagulant activity of endothelial cells after infection with respiratory viruses.
They may comprise triggering factors for the initiation and/ or acceleration of an ongoing inflammatory process by increased expression of adhesion molecules and inflammatory cytokines, procoagulant effects, increased receptor expression and activity, enhanced uptake of cholesterol and of modified low-density lipoprotein, increased smooth muscle cell migration and proliferation, anti-apoptotic effects, and autoimmune response to infection (4).