prochlorperazine


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Related to prochlorperazine: Cinnarizine, promethazine, metoclopramide, Betahistine, Prochlorperazine maleate, Stemetil

prochlorperazine

 [pro″klor-per´ah-zēn]
a phenothiazine derivative used as an antiemetic and sometimes as an antipsychotic agent; used as the base or as the edisylate or mesylate salts, administered orally, intravenously, intramuscularly, or rectally.

prochlorperazine

/pro·chlor·per·a·zine/ (pro″klor-per´ah-zēn) a phenothiazine derivative, used as the base or the edisylate or maleate salts as an antiemetic and antipsychotic.

prochlorperazine

(prō′klôr-pĕr′ə-zēn′)
n.
A phenothiazine drug, C20H24ClN3S, used to treat schizophrenia and anxiety and to stop or prevent vomiting.

prochlorperazine

[-klôrper′əzēn]
a phenothiazine antipsychotic and antiemetic.
indications It is prescribed in the treatment of psychotic disorders, and it may be used in the control of nausea and vomiting.
contraindications Parkinson's disease, the concurrent administration of central nervous system depressants, liver or renal dysfunction, severe hypotension, or known hypersensitivity to any phenothiazine prohibits its use.
adverse effects Among the more serious adverse effects are hypotension, liver toxicity, extrapyramidal reactions, blood dyscrasias, and hypersensitivity reactions.

prochlorperazine

Emezine® Oncology An antiemetic equivalent to Compazine® used for chemotherapy-related nausea

prochlorperazine

A PHENOTHIAZINE derivative antipsychotic drug used to treat SCHIZOPHRENIA and MANIA and to relieve nausea and vomiting. Brand names are Buccastem and Stemetil.

prochlorperazine

a phenothiazine derivative; the edisylate is used as a tranquilizer and antiemetic.
References in periodicals archive ?
along with his colleagues from Roseman University of Health Sciences, developed a preservative-free device-driven prochlorperazine nasal spray that could prove useful for compounding pharmacists specifically in the field of pain medicine.
Hyperemesis gravidarum, requires intravenous antiemetics, such as droperidol (Inapsine), prochlorperazine, and ondansetron.
We tried conventional approaches over the next 7 days (such as breath-holding) to interrupt the respiratory rhythm, continuous positive airway pressure, and pharmacotherapies with metoclopramine, prochlorperazine, chlorpromazine, haloperidol, mephenesin, diphenylhydantoin, baclofen, and phenobarbital, to no avail.
Other commonly used oral medications for NVP include prochlorperazine (Compazine), metoclopramide (Reglan), trimethobenzamide (Tigan), promethazine (Phenergan), and ondansetron (Zofran).
While effective, phenothiazines cause sedation, hypotension, and other side effects, he said, pointing out that prochlorperazine (Compazine) is not widely used because it is highly sedating.
Nausea may be mitigated if the drug is taken with food; if severe, it maybe treated with ondansetron (Zofran) or prochlorperazine (Compazine).
The PK studies required as part of the original NDA compared Emezine(R) to two reference listed drugs that included both the 5mg oral swallow tablet and the intravenous formulations of prochlorperazine (Emezine's(R) active ingredient).
IV prochlorperazine 5-10 mg given over 2 minutes every 6 hours.
Either prochlorperazine or placebo was used as the comparator.
Five dopamine antagonists--haloperidol, chlorpromazine, prochlorperazine, metoclopramide, and droperidol--have varying levels of evidence for their usefulness in treating acute migraine:
Tenders are invited for Tablet Prochlorperazine 5 Mg
Food and Drug Administration (FDA) for the company's new drug application (NDA) for Emezine(R), a buccal tablet formulation of prochlorperazine maleate for the treatment of severe nausea and vomiting.