procaspases


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procaspases

(prō'kas-pās-ĕz),
Inactive precursors of caspases.
See also: caspases.
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References in periodicals archive ?
Heat shock protein 70 inhibits apoptosis by preventing recruitment of procaspase 9 to the Apaf-1 apoptosome.
The mitochondria is the central regulator of the intrinsic pathway of apoptosis and that is accompanied by the release of procaspases, cytochrome c, apoptotic protease-activating factor 1 (Apaf-1), endonuclease G and apoptosis-inducing factor (Green 2000).
Caspase-8 then activates other procaspases, culminating in cleavage of cellular substrates, and apoptosis.