procarcinogen

procarcinogen

 [pro″kahr-sin´o-jen]
a chemical substance that becomes a carcinogen only after it is altered by metabolic processes.

procarcinogen

/pro·car·cin·o·gen/ (-kahr-sin″ah-jen) a chemical substance that becomes carcinogenic only after it is altered by metabolic processes.

procarcinogen

(prō″kar-sin′ŏ-jĕn) [ pro- + carcinogen]
An agent that may cause cancer only after it is metabolized within an organism.

procarcinogen

a chemical substance that becomes carcinogenic only after it is altered by metabolic processes.
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References in periodicals archive ?
2000), is a procarcinogen formed in the process of incomplete combustion of organic materials (Gelboin 1980).
Researchers from the University of California, San Diego School of Medicine, say the chemical disrupted liver integrity and compromised liver function in mice models that were given a procarcinogen to promote liver cancer.
That's right, and (very unfortunately for the men involved) my observation has been that many men who take finasteride to suppress procarcinogenic DHT end up suppressing their own anticarcinogenic 3 [beta] -Adiol even more, thus shifting the procarcinogen (DHT) to anticarcinogen (3 [beta] -Adiol) ratio toward a greater risk of cancer.
The studies clearly indicated that the administration of zinc in the presence of procarcinogen 1, 2 dimehtylhydrazine (DMH) brings about decrease in tumour incidence and tumour burden as well as profound alterations in the antioxidant status with restoration of normal colonic histoarchitecture.
However, the interactions between ethanol metabolism and procarcinogen metabolism are complex and may depend, among other factors, on the degree of CYP2E1 induction, the chemical structure of the procarcinogen, and the presence or absence of ethanol in the body during procarcinogen metabolism.
People with low CYP2A6 activity also seem to have a reduced risk for lung, gastric, oral, and colorectal cancers, because CYP2A6 is known to activate procarcinogen nitrosamines and other compounds in cigarette smoke into carcinogens.
Individuals with low CYP2A6 activity also appear to have a reduced risk for lung, gastric, oral, and colorectal cancers, because CYP2A6 is known to activate procarcinogen nitrosamines and other compounds in cigarette smoke into carcinogens.
Inter-individual differences in the ability of human milk-fat extracts to enhance the genotoxic potential of the procarcinogen benzo[a]pyrene in MCF-7 breast cells.
Human cytochrome P4502136: interindividual hepatic expression, substrate specificity, and role in procarcinogen activation.
44) They also suppress growth of bacteria that convert harmless procarcinogen molecules into carcinogens.
Epoxidation of (+/-)-7,8-dihydroxy-7,8-dihydrobenzo[[alpha]] pyrene during (bi)sulfite autoxidation: activation of a procarcinogen by a cocarcinogen.
This was achieved by inhibiting NADPH-cytochrome P450 reductase (Ki approximately 120 microM with cytochrome c as substrate), and did not involve lowering of the effective substrate concentration by complex formation with the procarcinogen.