CIA01

(redirected from probable cytosolic iron-sulphur protein assembly protein CIAO1)

CIA01

A gene on chromosome 2q11.2 that encodes a member of the WD-repeat protein family that is an essential component of the cytosolic iron-sulphur (Fe/S) protein assembly machinery, and is required for the maturation of extramitochondrial Fe/S proteins. CIA01 is thought to specifically modulate the transactivation activity of WT1; it may play a role in chromosome segregation as part of the mitotic spindle-associated MMXD complex.
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