In mice, the chemical lure for primordial germ cells is a protein known as stromal cell-derived factor-1 (SDF-1), Takashi Nagasawa of Kyoto University in Japan and his colleagues report in an upcoming Proceedings of the National Academy of Sciences.
Although these mice die as embryos, they live beyond the time when the gonads of normal mice are colonized by primordial germ cells.
We knew that with germ plasm pluripotency is not necessary, because the embryos contain primordial germ cells
stem cells from cultured porcine primordial germ cells
Debate continues over whether primordial germ cells
are the equivalent of blastocyst-derived stem cells.
Primordial germ cells
are one of only two types of cells known to be able to produce all of the more than 200 cell types found in the human body.
SCI is developing PluriCells[TM], a new human stem cell technology derived from primordial germ cells
of fetal tissue.
Kelly described biochemical characteristics of the cells that establish their similarity to human embryonic stem cells, human embryonic germ cells and human primordial germ cells
This research breakthrough came when we turned our attention to primordial germ cells
, the precursor cells to sperm and eggs," said Marie-Cecile van de Lavoir, senior scientist at Origen.
In the Hopkins research, scientists isolated primordial germ cells
(PGCs), cells that would form eggs and sperm, from human fetal tissue.