primordial germ cell


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pri·mor·di·al germ cell

the earliest undifferentiated sex cell, found initially outside the gonad.
Synonym(s): gonocyte

primordial germ cell

any of the large spheric diploid cells that are formed in the early stages of embryonic development and are precursors of the oogonia and spermatogonia. They are formed outside the gonads and migrate to the embryonic ovaries and testes for maturation. See also oogenesis, spermatogenesis.

primordial germ cell

A germ cell before it begins its maturation into a haploid gamete.
Synonym: primordial cell
See also: cell

primordial

original or primitive; of the simplest and most undeveloped character.

primordial germ cell
cells which provide the origins of the spermatozoa and the ovum; they originate from the yolk sac endoderm and migrate to the developing gonad.
References in periodicals archive ?
In mice, the chemical lure for primordial germ cells is a protein known as stromal cell-derived factor-1 (SDF-1), Takashi Nagasawa of Kyoto University in Japan and his colleagues report in an upcoming Proceedings of the National Academy of Sciences.
Although these mice die as embryos, they live beyond the time when the gonads of normal mice are colonized by primordial germ cells.
We knew that with germ plasm pluripotency is not necessary, because the embryos contain primordial germ cells anyway.
Debate continues over whether primordial germ cells are the equivalent of blastocyst-derived stem cells.
Primordial germ cells are one of only two types of cells known to be able to produce all of the more than 200 cell types found in the human body.
SCI is developing PluriCells[TM], a new human stem cell technology derived from primordial germ cells of fetal tissue.
Kelly described biochemical characteristics of the cells that establish their similarity to human embryonic stem cells, human embryonic germ cells and human primordial germ cells.
This research breakthrough came when we turned our attention to primordial germ cells, the precursor cells to sperm and eggs," said Marie-Cecile van de Lavoir, senior scientist at Origen.
In the Hopkins research, scientists isolated primordial germ cells (PGCs), cells that would form eggs and sperm, from human fetal tissue.