primary lysosomes

pri·mar·y ly·so·somes

lysosomes produced at the Golgi apparatus where hydrolytic enzymes are incorporated; they fuse with phagosomes or pinosomes to become secondary lysosomes.

azurophilic granule

A large, coarse, blue-purple membrane-bound organelle in progranulocytes, myelocytes and neutrophils, which acts as a reservoir for digestive and hydrolytic enzymes before delivery to a phagosome.

pri·mar·y ly·so·somes

(prī'mar-ē lī'sō-sōmz)
Lysosomes produced at the Golgi apparatus where hydrolytic enzymes are incorporated; they fuse with phagosomes or pinosomes to become secondary lysosomes.
References in periodicals archive ?
It was hypothesized that the electron-dense (type 1) granules were phagocytosed foreign materials (microorganisms, or other granules) or internal waste materials (organelles or fragments); the low electron-dense granules (type 2) primary lysosomes, probably originating in the Golgi complex or endoplasmic reticulum; and the medium electron-dense granules, secondary lysosomes, formed by fusion of type 1 and type 2 granules or matured by type 1 granules, which absorbed some hydrolytic enzymes.
Electron microscopy revealed scattered primary lysosomes in the cytoplasm of the leukemic cells, confirming their myeloid lineage.

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