primary lateral sclerosis


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.

pri·mar·y lat·er·al scle·ro·sis

considered by many to be a subgroup of motor neuron disease; a slowly progressive degenerative disorder of the motor neurons of the cerebral cortex, resulting in widespread weakness on an upper motor neuron basis; spasticity, hyperreflexia, and Babinski signs are present, but not fasciculation potentials, nor any electrodiagnostic evidence of a lower motor neuron lesion.

primary lateral sclerosis

a slowly progressing degenerative brain disease characterized by weakness, spasticity, hyperreflexia, and a positive Babinski sign. It involves neurons of the motor cortex but not the brainstem or spinal cord neurons. Also called spastic primary paraplegia.

pri·mar·y lat·er·al scle·ro·sis

(prī'mar-ē lat'ĕr-ăl skler-ō'sis)
Considered by many to be a subset of motor neuron disease; a slowly progressive degenerative disorder of the motor neurons of the cerebral cortex, resulting in widespread weakness on an upper motor neuron basis; spasticity, hyperreflexia, and Babinski sign are present, but not fasciculation potentials, nor any electrodiagnostic evidence of a lower motor neuron lesion.
Full browser ?